Adjust oven rack to middle position and heat oven to 350°F.
Whisk oil, garlic, salt, pepper, cayenne and chili powder together in a large bowl.
Add bread cubes and toss until coated.
Spread bread on baking sheet and bake until golden brown, 20 to 25 minutes.
Cool before serving.
*Makes about 4 cups*
**These can be stored in an airtight container for about 1 week.**